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In addition to causing weight loss resistance, high levels of leptin are also associated with high testosterone levels. Shbg levels can vary dramatically in response to oral estrogen dianabol steroids d-bol results and gains therapy following menopause or to oral contraceptives. Altman, Laurie Ashner Medline Plus US National Library of Medicine and the National Institutes of Health Androgen Insensitivity Syndrome Website: m Address: US National Library of Medicine 8601 Rockville Pike Bethesda, MD 20894 Email: email protected MD Consult Preview Website: ml? During puberty, it's normal for levels of estrogen to rise. The exact mechanism isn't clear, but there is definitely a correlation between progesterone/estrogen and testosterone. At menopause, women experience a decline in testosterone.